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  4. Horse Interleukin 8,IL-8 ELISA Kit

Horse Interleukin 8,IL-8 ELISA Kit

  • 中文名稱：
    馬白介素8(IL-8/CXCL8)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-E14021Hs
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    15.6 pg/mL-1000 pg/mL
  • 靈敏度：
    3.9 pg/mL
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥3800/￥2500
  • 促銷：
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    馬白介素8(IL-8/CXCL8)酶聯(lián)免疫試劑盒（CSB-E14021Hs）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CXCL8含量。CXCL8 即趨化因子配體 8，是一種重要的細(xì)胞因子。在炎癥反應(yīng)等生理病理過程中扮演關(guān)鍵角色。其機制主要是與相應(yīng)受體結(jié)合，激活下游信號通路，招募中性粒細(xì)胞等免疫細(xì)胞至炎癥部位，在感染、腫瘤等疾病研究中受關(guān)注。試劑盒檢測范圍為15.6 pg/mL-1000 pg/mL，適用于細(xì)胞因子網(wǎng)絡(luò)研究、藥物作用機制探索、疾病模型評估等科研領(lǐng)域，可兼容常規(guī)實驗室操作流程，為體外實驗、動物模型或臨床前研究提供可靠的IL - 8濃度檢測方案。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    CXCL8 ELISA Kit; IL8 ELISA Kit; Interleukin-8 ELISA Kit; IL-8 ELISA Kit; C-X-C motif chemokine 8 ELISA Kit; Chemokine ELISA Kit; C-X-C motif) ligand 8 ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Equus caballus (Horse)
  • 反應(yīng)時間：
    1-5h
  • 上樣量：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Immunology
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

引用文獻

產(chǎn)品評價

靶點詳情

  • 功能：
    IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus.
  • 基因功能參考文獻：
    1. Results suggested that chemokine expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses. PMID: 22280393
    2. Mapped six genes (EIF4G3, HSP90, RBBP6, IL8, TERT, and TERC) on the chromosomes of Equus caballus, Equus asinus, Equus grevyi, and Equus burchelli by fluorescence in situ hybridization. PMID: 21774619
    3. This study examined effects of in vitro exposure to solutions of hay dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction. PMID: 18052742
    4. These results suggest that MMP-1 and IL-8 are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon. PMID: 19552796
    5. The acute pulmonary neutrophilia characteristic of recurrent airway obstruction was not associated with an increase in expression of chemokines in pulmonary mononuclear cells from disease-susceptible horses. PMID: 19795943

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  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Intercrine alpha (chemokine CxC) family
  • 數(shù)據(jù)庫鏈接：