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G4S linker Monoclonal Antibody

  • 中文名稱:
    G4S linker CAR檢測工具
  • 貨號:
    CSB-MA186062I1m
  • 規格:
    ¥3000
  • 圖片:
    • The Binding Activity of G4S linker with Anti-G4S linker antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Three recombinant proteins containing G4S linker at 2 μg/mL can bind Anti-G4S linker antibody. The EC50 is 5.223 to 18.40 ng/mL, 17.89 to 45.51 ng/mL and 2.705 to 8.752 ng/mL.
    • Untransfected HEK-293F cells (green line) and transfected scFv-based Anti-CD19 CAR containing a G4S linker stable cells (red line) were stained with anti-G4S linker antibody (2μg/1*106cells), washed and then followed by APC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
  • 其他:

產品詳情

  • 產品描述:
    CUSABIO貨號:CSB-MA186062I1m人源G4S linker單克隆抗體是CAR-T細胞治療研究領域的高特異性檢測工具,專為識別嵌合抗原受體結構中的G4S柔性連接子設計。該抗體采用雜交瘤技術制備,可特異性結合CAR分子中連接抗體重鏈(VH)與輕鏈(VL)的關鍵結構域,適用于ELISA和流式細胞術(FC 1:50-1:200)兩種檢測平臺。作為通用型CAR陽性率檢測試劑,其核心價值在于支持CAR-X細胞療法(包括CAR-T、CAR-NK、CAR-M等)的研發質控環節,幫助科研人員精準評估工程化免疫細胞的CAR表達水平,為細胞制備工藝優化、功能驗證及體內外藥效研究提供可靠數據支撐。該產品嚴格滿足科研級抗體標準,尤其適用于腫瘤免疫治療基礎研究、新型CAR結構開發及細胞治療產品的臨床前研究體系驗證。
  • 基因名:
    G4S linker
  • 別名:
    G4S, G4S linker
  • 宿主:
    Mouse
  • 反應種屬:
    Homo sapiens (Human)
  • 免疫原:
    G4S-BSA
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Monoclonal
  • 抗體亞型:
    IgG2b
  • 純化方式:
    >95%, Protein G purified
  • 克隆號:
    11A12E7
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, FC
  • 推薦稀釋比:
    Application Recommended Dilution
    FC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價