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G4S linker Monoclonal Antibody

  • 中文名稱：
    G4S linker CAR檢測(cè)工具
  • 貨號(hào)：
    CSB-MA186062I2m
  • 規(guī)格：
    ￥3000
  • 圖片：
    • The Binding Activity of G4S linker with Anti-G4S linker antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Three recombinant proteins containing G4S linker at 2 μg/mL can bind Anti-G4S linker antibody. The EC50 is 10.03 to 17.44 ng/mL, 22.60 to 28.76 ng/mL and 6.478 to 10.27 ng/mL.
    • Untransfected HEK-293F cells (green line) and transfected scFv-based Anti-CD19 CAR containing a G4S linker stable cells (red line) were stained with anti-G4S linker antibody (2μg/1*106cells), washed and then followed by APC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CUSABIO貨號(hào)：CSB-MA186062I2m是針對(duì)G4S linker靶點(diǎn)的單克隆抗體，適用于人源樣本的ELISA和流式細(xì)胞術(shù)檢測(cè)，推薦使用稀釋比例為1:50-1:200（FC）。該抗體特異性識(shí)別嵌合抗原受體（CAR）結(jié)構(gòu)中連接輕鏈與重鏈的G4S柔性連接肽，作為CAR陽(yáng)性率檢測(cè)的關(guān)鍵工具，可廣泛應(yīng)用于CAR-T、CAR-NK等細(xì)胞療法的研發(fā)質(zhì)控環(huán)節(jié)。在基礎(chǔ)研究中，該抗體能高效定位CAR胞外結(jié)構(gòu)域，助力科研人員分析基因工程免疫細(xì)胞的表面表達(dá)效率、穩(wěn)定性及功能驗(yàn)證，為新型CAR細(xì)胞療法的開(kāi)發(fā)提供精準(zhǔn)檢測(cè)支持。產(chǎn)品采用雜交瘤技術(shù)制備，具有高批次穩(wěn)定性和低交叉反應(yīng)性，適用于細(xì)胞培養(yǎng)物、轉(zhuǎn)染樣本等實(shí)驗(yàn)體系中的CAR分子定量分析，是腫瘤免疫治療機(jī)制研究與細(xì)胞工程技術(shù)開(kāi)發(fā)的重要試劑。
  • 基因名：
    G4S linker
  • 別名：
    G4S, G4S linker
  • 宿主：
    Mouse
  • 反應(yīng)種屬：
    Homo sapiens (Human)
  • 免疫原：
    G4S-BSA
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    IgG2b
  • 純化方式：
    >95%, Protein G purified
  • 克隆號(hào)：
    12F11C10
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    FC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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