CDC42EP3 Antibody

產品詳情

Uniprot No.：

Q9UKI2
基因名：

CDC42EP3
別名：

CDC42EP3 antibody; BORG2 antibody; CEP3Cdc42 effector protein 3 antibody; Binder of Rho GTPases 2 antibody; MSE55-related Cdc42-binding protein antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the N-terminal region of Human Cdc42EP3.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:40000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
基因功能參考文獻：
1. Results provide evidence that Cdc42EP3 function in cancer-associated fibroblasts relies on tight regulation by Cdc42. PMID: 27248291
2. The expression of CDC42EP3 mRNA was significantly increased by 19.7% in dorsal prefrontal cortex in patient with schizophrenia. PMID: 20385374
亞細胞定位：

Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
蛋白家族：

BORG/CEP family
組織特異性：

Highly expressed in the heart and weakly in the brain.
數據庫鏈接：

HGNC: 16943

OMIM: 606133

KEGG: hsa:10602

STRING: 9606.ENSP00000295324

UniGene: Hs.369574