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  4. HOXD9 Antibody, FITC conjugated

HOXD9 Antibody, FITC conjugated

  • 中文名稱：
    HOXD9兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA010689LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HOXD9 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    homeobox D9 antibody; Homeobox protein Hox D9 antibody; Homeobox protein Hox-4C antibody; Homeobox protein Hox-5.2 antibody; Homeobox protein Hox-D9 antibody; Hox 4.3 antibody; Hox 5.2 antibody; HOX4 antibody; HOX4C antibody; HOXD9 antibody; HXD9_HUMAN antibody; RP23 313J15.10 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Homeobox protein Hox-D9 protein (38-276AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 基因功能參考文獻：
    1. HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma PMID: 26514226
    2. HoxD9 expression is regulated by histone acetylation in endothelial progenitor cells PMID: 25826494
    3. Data show that overexpressing homeobox D9 protein HOXD9 in mucinous ovarian carcinomas (MOCs)cells augmented the neoplastic phenotype PMID: 26075790
    4. The study investigates the temperature dependence of the internal motions of the lysine side-chain NH3(+) groups that form ion pairs with DNA phosphate groups in the HoxD9 homeodomain-DNA complex. PMID: 25489884
    5. Results show that melanoma patients with HOXD9 hypermethylation in lymph node metastasis had poorer disease-free and overall survival. PMID: 24014427
    6. A genome-wide array-comparative genomic hybridization (aCGH) analysis revealed global chromosomal aberration in MWCNTs-treated clones, predominantly at chromosome 2q31-32, where the potential oncogenes HOXD9 and HOXD13 are located PMID: 23984819
    7. The association between SNP of the HOXD9 gene and developmental hip dysplasia reached significance in Chinese Han females. PMID: 22520331
    8. Our results suggest that HOXD9 may be a novel marker of GCSCs and cell proliferation and/or survival factor in gliomas and glioma cancer stem-like cells, and a potential therapeutic target. PMID: 21600039
    9. 117-kb microdeletion removing HOXD9-HOXD13 and EVX2 causes synpolydactyly PMID: 11778160
    10. findings not only indicate that the HOXD9 gene is exclusively expressed in the rheumatoid arthritis synovium but also suggest that the HOXD9 gene contributes to the pathology of rheumatoid arthritis through the fibroblast-like synoviocytes PMID: 12060849
    11. HoxD9 and Pbx1 are inappropriately expressed in most human esophageal squamous cell carcinoma. Understanding the role of Hox genes in esophageal epithelial cell carcinogenesis may not only augment early detection but also offer possiblde treatment. PMID: 15770739

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Abd-B homeobox family
  • 數據庫鏈接：

    HGNC: 5140

    OMIM: 142982

    KEGG: hsa:3235

    STRING: 9606.ENSP00000249499

    UniGene: Hs.236646