POP4 Antibody

產品詳情

Uniprot No.：

O95707
基因名：

POP4
別名：

POP4 antibody; RPP29 antibody; Ribonuclease P protein subunit p29 antibody; hPOP4 antibody; EC 3.1.26.5 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human POP4
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
基因功能參考文獻：
1. Results demonstrate that Rpp29 promotes homology-directed repair of double-strand breaks. It is rapidly and transiently recruited to laser-microirradiated DNA sites. PMID: 28432356
2. Collectively, the present results suggest that PhoRpp21 binds the loop between P11 and P12 helices through overall positively charged clusters on the surface of the complex and serves as a scaffold for PhoRpp29 to optimize structural conformation of its N-terminal helix (alpha2) in PhoRpp21, as well as C-terminal residues in PhoRpp29, for RNase P activity. PMID: 27810361
3. Rpp29 represses H3.3 nucleosome deposition, a finding with implications for epigenetic regulation. PMID: 26842893
亞細胞定位：

Nucleus, nucleolus.
蛋白家族：

Eukaryotic/archaeal RNase P protein component 1 family
數據庫鏈接：

HGNC: 30081

OMIM: 606114

KEGG: hsa:10775

STRING: 9606.ENSP00000465213

UniGene: Hs.412870