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TGDS Antibody

  • 中文名稱：
    TGDS兔多克隆抗體
  • 貨號：
    CSB-PA023444LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA023444LA01HU diluted at 1:100 and staining in paraffin-embedded human stomach tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
    • IHC image of CSB-PA023444LA01HU diluted at 1:100 and staining in paraffin-embedded human Lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
    • Western Blot
      Positive WB detected in: HL-60 whole cell lysate(30μg), A431 whole cell lysate(30μg), 293 whole cell lysate(30μg), U251 whole cell lysate(30μg), HepG2 whole cell lysate(30μg), 786-O whole cell lysate(30μg), A549 whole cell lysate(30μg),Mouse Kidney tissue lysate(30μg),Rat Kidney tissue lysate(30μg)
      All lanes: TGDS antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/40000 dilution
      Predicted band size: 41 kDa
      Observed band size: 41 kDa
      Exposure time: 10s
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TGDS Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    6-dehydratase antibody; dTDP D glucose 4,6 dehydratase antibody; dTDP-D-glucose 4 antibody; Growth inhibiting protein 21 antibody; SDR2E1 antibody; TDP glucose 4,6 dehydratase antibody; TDPGD antibody; TGDS antibody; TGDS_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Synthesized peptide derived from TGDS
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. Our findings widen the phenotype spectrum caused by TGDS mutations and underline the phenotypic overlap with Temtamy preaxial brachydactyly syndrome. This improves our understanding of the prenatal development and the pathogenetic mechanism of Catel-Manzke syndrome. PMID: 28422407
    2. By using haplotype reconstruction we showed that the mutation c.298G>T is probably a founder mutation. Due to the spectrum of the amino acid changes, we suggest that loss of function in TGDS is the underlying mechanism of Catel-Manzke syndrome. PMID: 25480037
  • 相關疾病：
    Catel-Manzke syndrome (CATMANS)
  • 蛋白家族：
    NAD(P)-dependent epimerase/dehydratase family, dTDP-glucose dehydratase subfamily
  • 數據庫鏈接：

    HGNC: 20324

    OMIM: 616145

    KEGG: hsa:23483

    STRING: 9606.ENSP00000261296

    UniGene: Hs.12393