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AARS2

AARS2,即丙氨酰-tRNA合成酶2,別名mitochondrialalanyl-tRNAsynthetase2。它是由人類細胞中的AARS2基因編碼的一種蛋白質,主要在線粒體中發揮作用。AARS2的作用機制包括作為氨基酸轉運和蛋白質合成的關鍵酶,同時也是一種乳酸感受蛋白和乳酸化轉移酶,能夠感知L-乳酸積累,并通過乳酸化修飾調控其他蛋白的功能。AARS2不僅參與蛋白質合成,還參與調控固有免疫系統,影響病毒感染和免疫逃逸。AARS2的異常表達與多種癌癥相關,可能在癌癥發展中起到促進作用,并可作為評估預后和免疫治療反應的潛在生物標志物。

熱銷產品

AARS2 Antibody (CSB-PA953606)

驗證數據

CSB-PA953606

The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA953606(AARS2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA953606

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA953606(AARS2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA953606

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: SP20 cells, Primary antibody: CSB-PA953606(AARS2 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds

AARS2 Antibodies

AARS2 for Homo sapiens (Human)

AARS2 Proteins

AARS2 Proteins for Homo sapiens (Human)