ACKR2是一個編碼β趨化因子受體的基因，預測該蛋白質是與G蛋白偶聯受體類似的七次跨膜蛋白。該蛋白質在多種組織和造血細胞中表達。該受體在淋巴內皮細胞中的表達，以及在血管腫瘤中的過度表達，表明了它在趨化因子驅動的白細胞再循環和可能影響血管腫瘤發展和生長的趨化因子作用中的功能。新興證據表明，該蛋白質在銀屑病患者的炎癥變化中起著分子調節器的作用。
ACKR2 is a gene encoding a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. Emerging evidence has demonstrated that this protein plays a role in inflammatory changes in patients with psoriasis as a molecular regulator.