国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

AIFM1

Apoptosis-inducing factor 1, mitochondrial is a protein in humans that is encoded by AIFM1 gene. Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e. caspase-independent fragmentation of chromosomal DNA. Interacts with EIF3G,and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. Plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells. Binds to DNA in a sequence-independent manner.

AIFM1 Antibodies

AIFM1 for Homo sapiens (Human)

AIFM1 Proteins

AIFM1 Proteins for Homo sapiens (Human)

AIFM1 Proteins for Rattus norvegicus (Rat)

AIFM1 ELISA Kit

AIFM1 ELISA Kit for Homo sapiens (Human)