国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

ALCAM

活化白細(xì)胞黏附分子(ALCAM)又稱(chēng)CD166,是一種跨膜糖蛋白,屬于免疫球蛋白超家族成員。它在胚胎發(fā)育、神經(jīng)軸突導(dǎo)向及免疫細(xì)胞遷移中發(fā)揮關(guān)鍵作用,通過(guò)與受體相互作用介導(dǎo)同型或異型細(xì)胞黏附。ALCAM異常表達(dá)與多種腫瘤密切相關(guān),乳腺癌、結(jié)直腸癌中ALCAM高表達(dá)常伴隨侵襲轉(zhuǎn)移能力增強(qiáng),而前列腺癌中其表達(dá)缺失反而促進(jìn)腫瘤進(jìn)展,這種"雙刃劍"特性使其成為癌癥研究熱點(diǎn)。在神經(jīng)領(lǐng)域,阿爾茨海默病患者腦脊液中可檢測(cè)到ALCAM水平升高,提示其參與神經(jīng)炎癥過(guò)程。近年來(lái)針對(duì)ALCAR的靶向藥物研發(fā)集中在單克隆抗體方向,實(shí)驗(yàn)顯示阻斷ALCAM能抑制黑色素瘤細(xì)胞肺轉(zhuǎn)移。其復(fù)雜的功能網(wǎng)絡(luò)還涉及干細(xì)胞niche維持,在骨髓微環(huán)境中調(diào)控造血干細(xì)胞的定位與增殖。

熱銷(xiāo)產(chǎn)品

Recombinant Human CD166 antigen (ALCAM), partial (CSB-EP614444HU)

驗(yàn)證數(shù)據(jù)

CSB-EP614444HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ALCAM Recombinant Monoclonal Antibody (CSB-RA437652A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA437652A0HU

Western Blot
Positive WB detected in: PC3 whole cell lysate, HepG2 whole cell lysate, MCF-7 whole cell lysate, U251 whole cell lysate, A549 whole cell lysate, HEK293 whole cell lysate, Ntera-2 whole cell lysate, Mouse brain tissue
All lanes: ALCAM antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 66, 64, 16, 34 kDa
Observed band size: 100 kDa

CSB-RA437652A0HU

IHC image of CSB-RA437652A0HU diluted at 1:100 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.

CSB-RA437652A0HU

IHC image of CSB-RA437652A0HU diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.

ALCAM Antibodies

ALCAM for Homo sapiens (Human)

ALCAM Proteins

ALCAM Proteins for Gallus gallus (Chicken)

ALCAM Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

ALCAM Proteins for Oryctolagus cuniculus (Rabbit)

ALCAM Proteins for Rattus norvegicus (Rat)

ALCAM Proteins for Homo sapiens (Human)

ALCAM Proteins for Mus musculus (Mouse)

ALCAM Proteins for Carassius auratus (Goldfish)

ALCAM Proteins for Bos taurus (Bovine)

ALCAM ELISA Kit

ALCAM ELISA Kit for Homo sapiens (Human)



主站蜘蛛池模板: 大连市| 河西区| 平潭县| 高州市| 黄骅市| 德钦县| 林芝县| 山阳县| 全州县| 万安县| 巴青县| 舞钢市| 昭平县| 迭部县| 吉木乃县| 浦北县| 兴业县| 靖远县| 和政县| 蒙阴县| 金寨县| 阿克苏市| 公主岭市| 永嘉县| 庆城县| 焦作市| 琼结县| 亳州市| 南漳县| 黔江区| 沽源县| 尉氏县| 南阳市| 贞丰县| 赤城县| 道真| 那坡县| 佳木斯市| 利川市| 灵山县| 神池县|