ALDH18A1
ALDH18A1，即醛脫氫酶18家族成員A1，別名GSAS、P5CS、PYCS、SPG9、ADCL3、SPG9A、SPG9B、ARCL3A。ALDH18A1是一種雙功能酶，具有γ-谷氨酰激酶和γ-谷氨酰磷酸還原酶活性，依賴ATP和NADPH，主要位于線粒體中。ALDH18A1通過催化谷氨酸還原為δ1-吡咯-5-羧酸鹽，這是新生生物合成脯氨酸、鳥氨酸和精氨酸的關鍵步驟。ALDH18A1的突變可導致高氨血癥、鳥氨酸血癥、胱氨酸血癥、精氨酸血癥和脯氨酸血癥，可能與神經(jīng)退行性病變、白內(nèi)障和結締組織疾病相關。
熱銷產(chǎn)品
Recombinant Human Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) (CSB-EP001564HUe1)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ALDH18A1 Antibodies
ALDH18A1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA001564GA01HU | ALDH18A1 Antibody | Human,Mouse,Rat | ELISA,WB |
ALDH18A1 Proteins
ALDH18A1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001564HU CSB-EP001564HU CSB-BP001564HU CSB-MP001564HU CSB-EP001564HU-B |
Recombinant Human Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP001564HUe1 | Recombinant Human Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) | E.coli |
