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ARHGEF7

Rho guanine nucleotide exchange factor 7 is a protein in humans that is encoded by ARHGEF7 gene. Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

ARHGEF7 Antibodies

ARHGEF7 for Homo sapiens (Human)

ARHGEF7 Proteins

ARHGEF7 Proteins for Rattus norvegicus (Rat)

ARHGEF7 Proteins for Homo sapiens (Human)

ARHGEF7 Proteins for Mus musculus (Mouse)