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C1S

C1S,即補(bǔ)體成分1,s子成分,別名EDSPD2等。它來(lái)源于人體肝臟的合成,是血漿補(bǔ)體系統(tǒng)的重要組成部分。C1S作為絲氨酸蛋白酶,具有酶活性,能夠參與補(bǔ)體激活的典型途徑。當(dāng)抗原抗體復(fù)合物與C1q結(jié)合后,會(huì)激活C1r并相繼激活C1s,形成C1qr2s2復(fù)合物。這一激活過(guò)程進(jìn)一步引發(fā)補(bǔ)體級(jí)聯(lián)反應(yīng),導(dǎo)致炎癥的發(fā)生。C1S在免疫系統(tǒng)中起著關(guān)鍵的作用,它不僅是補(bǔ)體系統(tǒng)中的重要組分,還參與了免疫反應(yīng)的調(diào)控和炎癥的調(diào)節(jié)。通過(guò)對(duì)C1S的研究,可以深入了解補(bǔ)體系統(tǒng)的功能及其與疾病的關(guān)系,為相關(guān)疾病的防治提供理論基礎(chǔ)。

熱銷(xiāo)產(chǎn)品

Recombinant Human Complement C1s subcomponent (C1S) (CSB-EP003657HU)

驗(yàn)證數(shù)據(jù)

CSB-EP003657HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

C1S Recombinant Monoclonal Antibody (CSB-RA003657MA1HU)

驗(yàn)證數(shù)據(jù)

CSB-RA003657MA1HU

IHC image of CSB-RA003657MA1HU diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Human IgG labeled by HRP and visualized using 0.05% DAB.

Human Complement C1s subcomponent(C1S) ELISA kit (CSB-EL003657HU)

驗(yàn)證數(shù)據(jù)

CSB-EL003657HU 標(biāo)準(zhǔn)曲線(xiàn)

貨號(hào):CSB-EL003657HU

規(guī)格:96T/48T

靈敏度:6.25 ng/mL

檢測(cè)范圍:25 ng/mL-1600 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

C1S Antibodies

C1S for Homo sapiens (Human)

C1S Proteins

C1S Proteins for Homo sapiens (Human)

C1S Proteins for Bos taurus (Bovine)

C1S Proteins for Rattus norvegicus (Rat)

C1S ELISA Kit

C1S ELISA Kit for Homo sapiens (Human)