CD63
CD63，全稱為四跨膜蛋白3，常見別名包括LAMP3和ME491。它廣泛分布在細(xì)胞膜及細(xì)胞內(nèi)的囊泡結(jié)構(gòu)上，尤其在細(xì)胞外囊泡中含量較高，可幫助細(xì)胞之間傳遞信息，影響細(xì)胞的黏附、移動(dòng)等活動(dòng)。
在疾病領(lǐng)域，CD63的表達(dá)異常與多種癌癥相關(guān)，比如黑色素瘤、乳腺癌患者體內(nèi)它的水平常顯著升高，和腫瘤細(xì)胞的擴(kuò)散轉(zhuǎn)移存在聯(lián)系；此外，它在部分炎癥性疾病和自身免疫病中也有異常表現(xiàn)。藥物研發(fā)方面，目前CD63被視為癌癥診斷的潛在標(biāo)志物，針對(duì)它的抗體藥物也在早期研究階段，研究者希望通過靶向該蛋白來抑制腫瘤轉(zhuǎn)移，不過相關(guān)成果仍需更多臨床試驗(yàn)驗(yàn)證安全性與有效性。
熱銷產(chǎn)品
Recombinant Human CD63 antigen (CD63) (CSB-CF004950HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗(yàn)證數(shù)據(jù)
Western Blot analysis of SKOV3 cells using CD63 Polyclonal Antibody
Human cluster of differentiation 63,CD63 ELISA Kit (CSB-E14107h)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-E14107h
規(guī)格：96T/48T
靈敏度：0.156 ng/mL
檢測(cè)范圍：0.625 ng/mL-40 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CD63 Antibodies
CD63 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA006039 | CD63 Antibody | Human | WB, ELISA |
| CSB-PA080049 | CD63 Antibody | Human | IHC, ELISA |
| CSB-PA259468 | CD63 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA120615 | CD63 Antibody | Human | ELISA,WB,IHC |
| CSB-RA004950A0HU | CD63 Recombinant Monoclonal Antibody | Human | ELISA, IHC, IF |
| CSB-MA004950A0m | CD63 Monoclonal Antibody | Human | ELISA, WB, IHC, IF, FC |
| CSB-MA004950A1m | CD63 Monoclonal Antibody | Human, Rabbit | ELISA, WB, IHC, IF, FC |
CD63 Proteins
CD63 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-CF004950HU | Recombinant Human CD63 antigen (CD63) | in vitro E.coli expression system |
| CSB-EP004950HU1 | Recombinant Human CD63 antigen (CD63), partial | E.coli |
| CSB-BP004950HU1 CSB-MP004950HU1 CSB-EP004950HU1-B |
Recombinant Human CD63 antigen (CD63), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-YP004950HU1a4 | Recombinant Human CD63 antigen (CD63), partial | Yeast |
| CSB-YP004950HU1 | Recombinant Human CD63 antigen (CD63), partial | Yeast |
| CSB-MP004950HU | Recombinant Human CD63 antigen (CD63)-VLPs | Mammalian cell |
| CSB-MP004950HU(A4) | Recombinant Human CD63 antigen (CD63)-VLPs | Homo sapiens (Human) |
CD63 ELISA Kit
CD63 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E14107h | Human cluster of differentiation 63,CD63 ELISA Kit | serum, plasma, tissue homogenates | 0.156 ng/mL |
| CSB-E14107h-IS | Human cluster of differentiation 63,CD63 ELISA Kit | serum, plasma, cell culture supernates, urine, saliva, tissue homogenates | 23.5pg/ml |
