CEACAM1
CEACAM1，即癌胚抗原相關(guān)細(xì)胞黏附分子1，別名CD66a、BGP、C-CAM。CEACAM1由人類CEACAM1基因編碼，該基因位于19號(hào)染色體的q13.2位置。
CEACAM1通過(guò)與同源或異源配體的結(jié)合介導(dǎo)細(xì)胞黏附，影響多種細(xì)胞活動(dòng)，包括組織分化、血管生成、細(xì)胞凋亡、腫瘤抑制、轉(zhuǎn)移以及先天和適應(yīng)性免疫反應(yīng)的調(diào)節(jié)。
CEACAM1在阻止腫瘤生長(zhǎng)、上皮細(xì)胞增殖、誘導(dǎo)上皮細(xì)胞凋亡、調(diào)節(jié)免疫細(xì)胞功能等方面發(fā)揮著重要作用，其表達(dá)變化與多種疾病的發(fā)生發(fā)展相關(guān)，尤其在腫瘤免疫學(xué)領(lǐng)域。CEACAM1不僅可作為疾病的有效診斷標(biāo)記，還參與腫瘤的免疫逃逸，調(diào)控機(jī)體對(duì)腫瘤的免疫殺傷能力。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CEACAM1 at 2 μg/ml can bind Anti-CEACAM1 recombinant antibody(CSB-RA005157MA1HU). The EC50 is 3.432 - 6.079 ng/mL.
The purity of CEACAM1 was greater than 95% as determined by SEC-HPLC
CEACAM1 Recombinant Monoclonal Antibody (CSB-RA005157MA1HU)
驗(yàn)證數(shù)據(jù)
The Binding Activity of Human CEACAM1 with Anti-CEACAM1 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CEACAM1 at 2 μg/mL can bind Anti-CEACAM1 recombinant antibody(CSB-RA005157MA1HU). The EC50 is 3.432 - 6.079 ng/mL.
The Binding Activity of Human CEACAM1 with Anti-CEACAM1 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA.Immobilized Human CEACAM1(CSB-YP005157HU） at 2 μg/mL can bind Anti-CEACAM1 recombinant antibody. The EC50 is 0.3677-0.4528 ng/mL.
CEACAM1 Antibodies
CEACAM1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA005134 | CEACAM1 Antibody | Human | WB, ELISA |
| CSB-PA088258 | CEACAM1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA566314 | CEACAM1 Antibody | Human | ELISA,WB |
| CSB-PA815431 | CEACAM1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA939516 | CEACAM1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA10749A0Rb | CEACAM1 Antibody | Human | ELISA, WB, IF |
| CSB-PA10749D0Rb | CEACAM1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA10749C0Rb | CEACAM1 Antibody, FITC conjugated | Human | |
| CSB-PA10749B0Rb | CEACAM1 Antibody, HRP conjugated | Human | ELISA |
| CSB-RA147192A0HU | CEACAM1 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
| CSB-RA005157MA1HU | CEACAM1 Recombinant Monoclonal Antibody | Human | ELISA |
CEACAM1 Proteins
CEACAM1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-BP005157HU CSB-MP005157HU CSB-EP005157HU-B |
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005157HU(A4) | Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) | in vitro E.coli expression system |
| CSB-EP005157HU | Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), partial | E.coli |
| CSB-EP005157HUe1 | Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), partial | E.coli |
| CSB-MP005157HU-B | Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 1(CEACAM1),partial,Biotinylated (Active) | Mammalian cell |
| CSB-EP005157HUd7 | Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), partial | E.coli |
| CSB-YP005157HU | Recombinant Human Cell adhesion molecule CEACAM1 (CEACAM1), partial (Active) | Yeast |
CEACAM1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP005157RA1 CSB-EP005157RA1 CSB-BP005157RA1 CSB-MP005157RA1 CSB-EP005157RA1-B |
Recombinant Rat Carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005157RA | Recombinant Rat Carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) | in vitro E.coli expression system |
CEACAM1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP005157MO1 CSB-EP005157MO1 CSB-BP005157MO1 CSB-MP005157MO1 CSB-EP005157MO1-B |
Recombinant Mouse Carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005157MO | Recombinant Mouse Carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) | in vitro E.coli expression system |
CEACAM1 ELISA Kit
CEACAM1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL005157HU | Human Carcinoembryonic antigen-related cell adhesion molecule 1(CEACAM1) ELISA kit | serum, plasma, tissue homogenates | 0.195 ng/mL |
