国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

DDB2

DNA damage-binding protein 2 is a protein in humans that is encoded by DDB2 gene. Required for DNA repair. Binds to DDB1 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also appears to function as the substrate recognition module for the DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex DDB1-CUL4-ROC1 (also known as CUL4-DDB-ROC1 and CUL4-DDB-RBX1). The DDB1-CUL4-ROC1 complex may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair. The DDB1-CUL4-ROC1 complex also ubiquitinates XPC, which may enhance DNA-binding by XPC and promote NER. Isoform D1 and isoform D2 inhibit UV-damaged DNA repair.

DDB2 Antibodies

DDB2 for Homo sapiens (Human)

DDB2 Proteins

DDB2 Proteins for Bos taurus (Bovine)

DDB2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

DDB2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

DDB2 Proteins for Gallus gallus (Chicken)

DDB2 Proteins for Arabidopsis thaliana (Mouse-ear cress)

DDB2 Proteins for Homo sapiens (Human)

DDB2 Proteins for Mus musculus (Mouse)



主站蜘蛛池模板: 海伦市| 康马县| 崇左市| 类乌齐县| 钦州市| 奎屯市| 兰溪市| 郯城县| 昌图县| 乌拉特后旗| 宁化县| 乌海市| 浦北县| 共和县| 德令哈市| 七台河市| 湘潭县| 大邑县| 盐津县| 长泰县| 青冈县| 沧州市| 通渭县| 德钦县| 孝昌县| 都安| 十堰市| 茌平县| 苏尼特左旗| 霍州市| 许昌县| 许昌市| 蛟河市| 鹰潭市| 郸城县| 塔河县| 丰台区| 基隆市| 涿鹿县| 繁昌县| 三原县|