DDX3X（DEAD-box helicase 3 X-linked）屬于DEAD-box蛋白家族的蛋白基因，是一種RNA依賴性ATP酶/蛋白質(zhì)解旋酶。包含特定的結(jié)構(gòu)域，如DEAD-box域，它們對于核酸解旋和RNA結(jié)合至關(guān)重要。DDX3X蛋白在細(xì)胞中參與多種生物學(xué)過程，包括轉(zhuǎn)錄調(diào)節(jié)、RNA穩(wěn)定性、翻譯調(diào)節(jié)和信號轉(zhuǎn)導(dǎo)等。它通過解旋RNA二級結(jié)構(gòu)，參與mRNA的轉(zhuǎn)錄和翻譯調(diào)控，并在細(xì)胞周期、凋亡和免疫反應(yīng)中發(fā)揮作用。DDX3X在多種癌癥中的異常表達(dá)與腫瘤發(fā)生和發(fā)展相關(guān)。研究表明它在調(diào)節(jié)癌細(xì)胞增殖和轉(zhuǎn)移中起重要作用，此外，一些病毒依賴于DDX3X來完成它們的生命周期。因此，DDX3X作為一個(gè)在細(xì)胞生物學(xué)中具有重要功能的蛋白，對于癌癥和病毒感染等研究有著重要意義，研究DDX3X在病毒感染過程中的作用也有助于開發(fā)新的抗病毒策略。

熱銷產(chǎn)品

● Recombinant Human ATP-dependent RNA helicase DDX3X (DDX3X)

驗(yàn)證數(shù)據(jù)

SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LC-MS/MS

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP006621HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) DDX3X.

LC-MS/MS

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP006621HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) DDX3X.