ELAVL4
ELAVL4，全稱為ELAV樣RNA結合蛋白4，常用別名是HuD。它是一種主要分布在神經系統中的RNA結合蛋白，與神經細胞的發育、成熟及突觸功能的維持密切相關。正常情況下，HuD能幫助某些神經相關的遺傳信息分子保持穩定，確保這些分子順利轉化為蛋白質，從而支持神經細胞的生長分化和信號傳遞。
當HuD的表達或功能出現異常時，可能與多種疾病相關。比如阿爾茨海默病患者的腦組織中，HuD的水平常發生變化，影響神經細胞的正常運作；在神經母細胞瘤等腫瘤中，它的異常表達也可能促進腫瘤細胞的增殖。目前，科研人員正在探索調控HuD活性的策略，例如通過小分子化合物或核酸類物質調整其功能，希望為相關疾病的治療提供新方向。
熱銷產品
Recombinant Human ELAV-like protein 4 (ELAVL4) (CSB-EP007595HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ELAVL4 Antibody (CSB-PA007595LA01HU)
驗證數據
Western blot
All lanes: ELAVL4 antibody at 2µg/ml
Lane 1: MCF-7 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 42, 41, 43 kDa
Observed band size: 42 kDa
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA007595LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA007595LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA007595LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
ELAVL4 Antibodies
ELAVL4 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA007595GA01HU | ELAVL4 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA007595LA01HU | ELAVL4 Antibody | Human | ELISA, WB, IHC, IF |
ELAVL4 Proteins
ELAVL4 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007595HU CSB-BP007595HU CSB-MP007595HU CSB-EP007595HU-B |
Recombinant Human ELAV-like protein 4 (ELAVL4) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
