FLNB
FLNB，全稱為Filamin B，也叫β-細絲蛋白，是細胞骨架的關鍵成員之一。它能串聯細胞內的肌動蛋白纖維，支撐細胞形態結構，還參與細胞移動、分化等過程，在骨骼和結締組織發育中扮演重要角色。FLNB功能異常，可能引發多種骨骼發育疾病，比如青少年特發性脊柱側凸、胸廓畸形，以及罕見的遺傳性骨發育不全（如atelosteogenesisⅡ/Ⅲ型）、回飛鏢樣發育不良等，這些疾病多與FLNB的結構突變相關。目前針對FLNB相關疾病的治療仍在探索階段，研究人員嘗試用小分子調節蛋白間的相互作用，或通過基因編輯修復突變位點，但這些策略大多處于實驗室研究或早期臨床試驗階段。
熱銷產品
Recombinant Human Filamin-B (FLNB), partial (CSB-EP008725HU1)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
FLNB Antibodies
FLNB for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA008725GA01HU | FLNB Antibody | Human,Mouse,Rat | ELISA,WB,IF |
FLNB Proteins
FLNB Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP008725HU CSB-EP008725HU CSB-BP008725HU CSB-MP008725HU CSB-EP008725HU-B |
Recombinant Human Filamin-B (FLNB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP008725HU1 | Recombinant Human Filamin-B (FLNB), partial | E.coli |
| CSB-EP008725HU1(M) | Recombinant Human Filamin-B (FLNB) (T2177A,V2354A,R2374A), partial | E.coli |
FLNB Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP800356MO CSB-EP800356MO CSB-BP800356MO CSB-MP800356MO CSB-EP800356MO-B |
Recombinant Mouse Filamin-B (Flnb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FLNB Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP885623RB CSB-EP885623RB CSB-BP885623RB CSB-MP885623RB CSB-EP885623RB-B |
Recombinant Rabbit Filamin-B (FLNB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
