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GPR55

GPR55,即G蛋白偶聯受體55,別名LPI1、GPR55、PSIGPR53。GPR55由人類GPR55基因編碼,該基因位于2號染色體的q37.1區域。GPR55是一種G蛋白偶聯受體,可能通過激活多種信號轉導通路參與多種生理和病理過程。它被激活的配體包括植物性大麻素、內源性大麻素以及溶血磷脂酰肌醇(LPI)。GPR55與情緒、運動、認知、學習和記憶等生理功能相關,同時也與大麻素的作用以及藥物濫用有關。GPR55還可能成為治療炎癥、疼痛、糖尿病、帕金森病、神經病理性疼痛和癌癥的新潛在藥物靶點。研究表明,GPR55在調節焦慮樣行為、海馬神經發生以及神經保護方面發揮作用。

熱銷產品

GPR55 Antibody (CSB-PA009820OA01HU)

驗證數據

CSB-PA009820OA01HU

IHC image of CSB-PA009820OA01HU diluted at 1:100 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

GPR55 Antibodies

GPR55 for Homo sapiens (Human)

GPR55 Proteins

GPR55 Proteins for Mus musculus (Mouse)