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GSDME

GSDME,別名DFNA5、ICERE-1。它來源于人體細胞,是一種具有膜穿孔活性的蛋白質。GSDME在細胞中的作用機制主要是通過被Caspase 3切割激活,誘導細胞從凋亡向細胞焦亡轉換。在生物學上,GSDME具有多重意義,包括參與神經退行性疾病的發生、調節炎癥反應,以及作為癌癥免疫療法的潛在靶點。它的發現和研究為理解細胞死亡機制、治療神經退行性疾病和癌癥提供了新的視角和策略。

熱銷產品

Recombinant Human Gasdermin-E (GSDME) (CSB-EP006766HU)

驗證數據

CSB-EP006766HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

GSDME Antibody (CSB-PA006766LA01HU)

驗證數據

CSB-PA006766LA01HU

Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA006766LA01HU at dilution of 1:100

CSB-PA006766LA01HU

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA006766LA01HU at dilution of 1:100

CSB-PA006766LA01HU

Immunofluorescent analysis of Hela cells using CSB-PA006766LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

GSDME Antibodies

GSDME for Homo sapiens (Human)

GSDME Proteins

GSDME Proteins for Homo sapiens (Human)