GSTZ1
GSTZ1，全稱為谷胱甘肽S-轉移酶ζ1，常用別名包括馬來酰乙酰乙酸異構酶。它是人體酪氨酸代謝中的關鍵參與者，能促進代謝過程里某類中間物質的轉化，讓酪氨酸的分解代謝得以正常完成。一旦GSTZ1功能出現問題，代謝產物會在體內積累，從而引發遺傳性酪氨酸血癥I型，患者可能出現肝臟受損、腎功能異常等多種癥狀。在臨床治療上，尼替西農是常用藥物之一，它通過調節代謝通路的上游步驟，減少有毒物質的產生，幫助緩解患者癥狀。目前針對該蛋白缺陷的新療法，比如酶替代治療或基因相關干預，仍處于早期研發階段，未來可能為這類疾病提供更有效的治療方案。
熱銷產品
GSTZ1 Monoclonal Antibody (CSB-MA554791)
驗證數據
Flow cytometric analysis of GSTZ1 expression in HeLa cells using GSTZ1 antibody. Green, isotype control; red, GSTZ1.
Western blotting analysis using GSTZ1 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with GSTZ1 antibody and HRP-conjugated goat mouse secondary antibody respectively.
GSTZ1 Antibody (CSB-PA009994DSR1HU)
驗證數據
Western blot
All lanes: GSTZ1 antibody at 0.41μg/ml + Mouse liver tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 25, 18, 20 kDa
Observed band size: 25 kDa
Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA009994DSR1HU at dilution of 1:100
GSTZ1 Antibodies
GSTZ1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA009994GA01HU | GSTZ1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA009994DSR1HU | GSTZ1 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA009994DSR2HU | GSTZ1 Antibody | Human | ELISA, IHC |
| CSB-MA554791 | GSTZ1 Monoclonal Antibody | Human | ELISA, WB, FC |
GSTZ1 Proteins
GSTZ1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009994HU CSB-BP009994HU CSB-MP009994HU CSB-EP009994HU-B |
Recombinant Human Maleylacetoacetate isomerase (GSTZ1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP009994HU | Recombinant Human Maleylacetoacetate isomerase (GSTZ1) | E.coli |
