HNRNPH1
HNRNPH1,全稱為異質核核糖核蛋白H1,常用別名包括hnRNP H、HNRPH1等。作為細胞內重要的RNA結合蛋白,它能與多種RNA分子結合,參與調控RNA的剪接、轉運及穩定性維持,在細胞正常生理活動中發揮核心作用。HNRNPH1異常表達或功能改變與多種疾病關聯緊密:在神經系統中,它可能干擾神經細胞的RNA代謝,與脆性X相關震顫/共濟失調綜合征等疾病的發生有關;在腫瘤領域,它的高表達常見于乳腺癌、肺癌等惡性腫瘤,或推動腫瘤細胞增殖與轉移。目前針對該蛋白的藥物研發尚處早期,科研人員正嘗試開發靶向其RNA結合活性的小分子抑制劑,或干擾其與其他分子的相互作用來調節功能,雖暫未進入臨床階段,但為相關疾病治療提供了新的探索方向。
熱銷產品
Recombinant Human Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) (CSB-EP010609HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP010609HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) HNRNPH1.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP010609HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) HNRNPH1.
HNRNPH1 Monoclonal Antibody (CSB-MA058347)
驗證數據
Flow cytometric analysis of HNRNPH1 expression in HeLa cells using HNRNPH1 antibody. Green, isotype control; red, HNRNPH1.
Western blotting analysis using HNRNPH1 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with HNRNPH1 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
HNRNPH1 Antibody (CSB-PA04264A0Rb)
驗證數據
Western blot
All lanes: HNRNPH1 antibody at 2µg/ml
Lane 1: EC109 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/15000 dilution
Predicted band size: 50 kDa
Observed band size: 36 kDa
HNRNPH1 Antibodies
HNRNPH1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA04264A0Rb | HNRNPH1 Antibody | Human | ELISA, WB |
| CSB-PA04264D0Rb | HNRNPH1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA010609GA01HU | HNRNPH1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA010609HD01HU | HNRNPH1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA010609HA01HU | HNRNPH1 Antibody | Human | ELISA, WB, IHC |
| CSB-PA046570 | HNRNPH1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA786287 | HNRNPH1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-MA058347 | HNRNPH1 Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB, FC |
HNRNPH1 Proteins
HNRNPH1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP010609HU CSB-BP010609HU CSB-MP010609HU CSB-EP010609HU-B |
Recombinant Human Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP010609HU2 | Recombinant Human Heterogeneous nuclear ribonucleoprotein H (HNRNPH1), partial | E.coli |
| CSB-EP010609HU | Recombinant Human Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) | E.coli |






