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HTRA2

Serine protease HTRA2, mitochondrial is a protein in humans that is encoded by HTRA2 gene. Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.

HTRA2 Antibodies

HTRA2 for Homo sapiens (Human)

HTRA2 Proteins

HTRA2 Proteins for Bos taurus (Bovine)

HTRA2 Proteins for Homo sapiens (Human)

HTRA2 Proteins for Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)

HTRA2 Proteins for Drosophila ananassae (Fruit fly)

HTRA2 Proteins for Drosophila virilis (Fruit fly)

HTRA2 Proteins for Drosophila mojavensis (Fruit fly)

HTRA2 Proteins for Drosophila erecta (Fruit fly)

HTRA2 Proteins for Drosophila persimilis (Fruit fly)

HTRA2 Proteins for Drosophila sechellia (Fruit fly)

HTRA2 Proteins for Drosophila willistoni (Fruit fly)

HTRA2 Proteins for Drosophila yakuba (Fruit fly)

HTRA2 Proteins for Drosophila simulans (Fruit fly)

HTRA2 Proteins for Drosophila pseudoobscura pseudoobscura (Fruit fly)

HTRA2 Proteins for Mus musculus (Mouse)

HTRA2 Proteins for Drosophila melanogaster (Fruit fly)