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IL5RA

IL5RA,即白細胞介素5受體亞單位α,它是一種主要表達在單核細胞、T細胞和B細胞等免疫細胞表面的細胞因子受體。IL5RA的作用機制是與IL-5配體結合,形成α鏈和β鏈的異二聚體受體復合物,進而激活下游的信號傳導途徑,如JAK/STAT、MAPK、PI3K和NF-κB等,調節免疫細胞的增殖、分化和功能。IL5RA對調節免疫應答、細胞分化和炎癥反應等生理過程至關重要,其異常表達或功能失調與多種疾病,包括腫瘤、炎癥和自身免疫性疾病的發生發展密切相關。

熱銷產品

IL5RA Antibody (CSB-PA547751)

驗證數據

CSB-PA547751

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA547751(IL5RA Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA547751

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA547751(IL5RA Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA547751

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA547751(IL5RA Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes

IL5RA Antibodies

IL5RA for Homo sapiens (Human)

IL5RA Proteins

IL5RA Proteins for Mus musculus (Mouse)