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ITGA2

ITGA2,即整合素α2亞基,別名CD49b、GPIa、HPA-5、VLA-2,是一種150 kDa的膜表面糖蛋白,在多種細胞類型中表達,如血小板、腸上皮細胞、NK細胞、上皮細胞和活化T細胞等。
ITGA2的作用機制是與CD29(整合素β1)非共價結合形成異質二聚體VLA-2,即血小板糖蛋白Ia/IIa (CD49b/CD29),介導成熟巨核細胞和血小板與膠原之間的粘附。ITGA2在細胞外基質細胞粘附中起著重要作用,參與細胞粘附、遷移、增殖和信號傳導等過程,對維持組織結構和功能完整性至關重要。異常的ITGA2表達與多種疾病相關,包括多種動脈疾病、血小板疾病、糖尿病等。

熱銷產品

Recombinant Human Integrin alpha-2 (ITGA2), partial (CSB-EP011864HUb0)

驗證數據

CSB-EP011864HUb0

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ITGA2 Antibody (CSB-PA006197)

驗證數據

CSB-PA006197

Western Blot analysis of 3T3 cells using Integrin α2 Polyclonal Antibody

CSB-PA006197

Western Blot analysis of NIH-3T3 cells using Integrin α2 Polyclonal Antibody

Human Integrin alpha-2(ITGA2) ELISA kit (CSB-EL011864HU)

驗證數據

CSB-EL011864HU 標準曲線

貨號:CSB-EL011864HU

規格:96T/48T

靈敏度:0.058 ng/mL

檢測范圍:0.235 ng/mL-15 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ITGA2 Antibodies

ITGA2 for Homo sapiens (Human)

ITGA2 Proteins

ITGA2 Proteins for Homo sapiens (Human)

ITGA2 Proteins for Bos taurus (Bovine)

ITGA2 Proteins for Mus musculus (Mouse)

ITGA2 ELISA Kit

ITGA2 ELISA Kit for Homo sapiens (Human)