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JAG2

JAG2蛋白,全名為Jagged-2,是一種在人體中由JAG2基因編碼的蛋白質(zhì)。它也被稱為Jagged canonical Notch ligand 2。JAG2蛋白在細(xì)胞信號(hào)傳導(dǎo)中扮演重要角色,尤其是在Notch信號(hào)通路中。該通路對于胚胎發(fā)育和細(xì)胞命運(yùn)決定至關(guān)重要。JAG2蛋白與Notch受體結(jié)合,激活信號(hào)通路,從而影響細(xì)胞生長、分化和存活。在疾病方面,JAG2蛋白的異常表達(dá)與多種疾病有關(guān),包括癌癥。近年來,針對JAG2蛋白的藥物研發(fā)取得了進(jìn)展,有望為相關(guān)疾病的治療提供新的策略。

熱銷產(chǎn)品

JAG2 Antibody (CSB-PA049990)

驗(yàn)證數(shù)據(jù)

CSB-PA049990

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA049990(JAG2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA049990

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA049990(JAG2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

JAG2 Antibodies

JAG2 for Homo sapiens (Human)

JAG2 Proteins

JAG2 Proteins for Rattus norvegicus (Rat)

JAG2 Proteins for Mus musculus (Mouse)