KIR2DL2
KIR2DL2，全稱為殺傷細(xì)胞免疫球蛋白樣受體2DL2，也被稱為NKAT6、p58.2、CD158b1。該蛋白是一種跨膜糖蛋白，屬于殺傷細(xì)胞免疫球蛋白樣受體（KIR）家族。KIR2DL2主要表達(dá)在自然殺傷（NK）細(xì)胞和部分T細(xì)胞上，通過識(shí)別HLA-C類分子來調(diào)節(jié)NK細(xì)胞的活化和抑制。它能夠抑制NK細(xì)胞的細(xì)胞毒性作用，從而防止正常細(xì)胞被錯(cuò)誤地攻擊。KIR2DL2與多種疾病相關(guān)，包括癌癥、自身免疫性疾病等。在藥物研發(fā)方面，針對(duì)KIR2DL2的抗體已被開發(fā)出來，用于治療某些癌癥和自身免疫性疾病。
熱銷產(chǎn)品
KIR2DL2 Antibody (CSB-PA012353LA01HU)
驗(yàn)證數(shù)據(jù)
Immunofluorescence staining of A549 cells with CSB-PA012353LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
KIR2DL2 Antibodies
KIR2DL2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA012353LA01HU | KIR2DL2 Antibody | Human | ELISA, IF |
| CSB-PA012353LB01HU | KIR2DL2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA012353LC01HU | KIR2DL2 Antibody, FITC conjugated | Human |
KIR2DL2 Proteins
KIR2DL2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012353HU1 CSB-EP012353HU1 CSB-BP012353HU1 CSB-MP012353HU1 CSB-EP012353HU1-B |
Recombinant Human Killer cell immunoglobulin-like receptor 2DL2 (KIR2DL2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012353HU | Recombinant Human Killer cell immunoglobulin-like receptor 2DL2 (KIR2DL2) | in vitro E.coli expression system |
