国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

MARK2

MARK2 is a protein in humans that is encoded by MARK2 gene. Serine/threonine-protein kinase. Involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4 and RAB11FIP2. Phosphorylates the microtubule-associated protein MAPT/TAU. Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Regulates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Regulates axogenesis by phosphorylating KIF13B, promoting interaction between KIF13B and 14-3-3 and inhibiting microtubule-dependent accumulation of KIF13B. Also required for neurite outgrowth and establishment of neuronal polarity. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).

MARK2 Antibodies

MARK2 for Homo sapiens (Human)

MARK2 Proteins

MARK2 Proteins for Mus musculus (Mouse)

MARK2 Proteins for Rattus norvegicus (Rat)

MARK2 Proteins for Homo sapiens (Human)



主站蜘蛛池模板: 满洲里市| 渭源县| 若尔盖县| 元氏县| 建德市| 抚宁县| 峨边| 平定县| 原阳县| 荥经县| 新乐市| 翁牛特旗| 南皮县| 株洲市| 舞阳县| 开阳县| 明溪县| 威信县| 镇巴县| 宁国市| 永新县| 抚远县| 眉山市| 长宁区| 黎城县| 阳谷县| 康保县| 新干县| 柘城县| 临泽县| 逊克县| 眉山市| 古丈县| 遵化市| 阿巴嘎旗| 安阳市| 介休市| 岳池县| 鹰潭市| 灵寿县| 上蔡县|