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MEF2D

MEF2D,即肌細胞增強因子2D,別名Myocyte enhancer factor 2D。它是MADS盒家族的成員之一,參與多種細胞生命活動的調控。它通過與DNA上的MEF2結合位點相互作用,調控下游基因的轉錄,影響細胞增殖、分化、遷移和凋亡等過程。MEF2D在肌肉生成、神經系統發育、肝纖維化以及腫瘤發展中扮演重要角色。特別是在腫瘤生物學中,MEF2D的異常表達與多種腫瘤的侵襲性、轉移能力和患者預后密切相關,使其成為癌癥治療的潛在靶點。

熱銷產品

MEF2D Antibody (CSB-PA613522LA01HU)

驗證數據

CSB-PA613522LA01HU

Western Blot
Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, Mouse heart tissue
All lanes: MEF2D antibody at 2.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 56, 57, 51, 50 kDa
Observed band size: 56 kDa

CSB-PA613522LA01HU

IHC image of CSB-PA613522LA01HU diluted at 1:400 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA613522LA01HU

IHC image of CSB-PA613522LA01HU diluted at 1:400 and staining in paraffin-embedded human melanoma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

MEF2D Antibodies

MEF2D for Homo sapiens (Human)

MEF2D Proteins

MEF2D Proteins for Rattus norvegicus (Rat)

MEF2D Proteins for Homo sapiens (Human)

MEF2D Proteins for Mus musculus (Mouse)