MLKL
MLKL（mixed lineage kinase domain-like）是與細胞凋亡相關的蛋白質。其激活狀態涉及到其N-末端結構域的磷酸化，這種磷酸化導致MLKL的構象變化，從而促使其進入細胞膜，并引發細胞壞死。特別是在程序性壞死性細胞死亡（necroptosis）中發揮作用。在細胞受到特定信號刺激時，MLKL促進程序性壞死性細胞死亡，這種細胞死亡與免疫應答、炎癥和組織修復等生物學過程有關。在疾病治療領域中。，其磷酸化狀態和活性受到廣泛關， 對MLKL的研究對于了解壞死性細胞死亡的分子機制，尤其是在免疫相關疾病和炎癥性疾病中發揮的作用，以及尋找相關的治療策略非常重要。
熱銷產品
Recombinant Human Mixed lineage kinase domain-like protein (MLKL)
驗證數據
SDS-PAGE
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
MLKL Antibodies
MLKL for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA850851LA01HU | MLKL Antibody | Human | ELISA, IHC |
| CSB-PA850851LC01HU | MLKL Antibody, FITC conjugated | Human | |
| CSB-PA003250 | MLKL Antibody | Human | WB, ELISA |
| CSB-RA850851A358phHU | Phospho-MLKL (S358) Recombinant Monoclonal Antibody | Human | ELISA, IHC |
MLKL Proteins
MLKL Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP850851HU | Recombinant Human Mixed lineage kinase domain-like protein (MLKL) | Yeast |
| CSB-EP850851HU | Recombinant Human Mixed lineage kinase domain-like protein (MLKL) | E.coli |
| CSB-BP850851HU CSB-MP850851HU CSB-EP850851HU-B |
Recombinant Human Mixed lineage kinase domain-like protein (MLKL) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP850851HUb2 | Recombinant Human Mixed lineage kinase domain-like protein (MLKL) | E.coli |
MLKL Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP861529MO | Recombinant Mouse Mixed lineage kinase domain-like protein (Mlkl) | Yeast |
| CSB-EP861529MO CSB-BP861529MO CSB-MP861529MO CSB-EP861529MO-B |
Recombinant Mouse Mixed lineage kinase domain-like protein (Mlkl) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MLKL Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP850851HUa0 | Recombinant Human Mixed lineage kinase domain-like protein (MLKL) | E.coli |
