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PMAIP1

Phorbol-12-myristate-13-acetate-induced protein 1 is a protein in humans that is encoded by PMAIP1 gene. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

PMAIP1 Antibodies

PMAIP1 for Homo sapiens (Human)

PMAIP1 Proteins

PMAIP1 Proteins for Rattus norvegicus (Rat)

PMAIP1 Proteins for Mus musculus (Mouse)

PMAIP1 Proteins for Homo sapiens (Human)

PMAIP1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)