PRF1
PRF1，即穿孔素1，常見別名有PFP、細胞毒性穿孔蛋白。它主要存在于細胞毒性T淋巴細胞和自然殺傷細胞中，是這些免疫細胞清除異常細胞的核心分子之一。當免疫細胞識別到病毒感染細胞或腫瘤細胞時，穿孔素1會被釋放到靶細胞表面，形成跨膜孔道，助力后續效應分子進入靶細胞內部，從而清除異常細胞。若該蛋白功能異常，免疫細胞的殺傷能力會下降，易引發家族性噬血細胞性淋巴組織細胞增多癥，部分淋巴瘤、自身免疫病的發生也與它相關。目前針對相關疾病，造血干細胞移植是常用治療手段，同時科研人員也在探索靶向調節免疫細胞活性的藥物，以改善穿孔素1相關的免疫功能紊亂問題。
熱銷產品
Recombinant Human Perforin-1 (PRF1) (CSB-BP018668HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human Perforin-1 (PRF1/PFP) ELISA kit (CSB-E09313h-IS)
驗證數據
貨號：CSB-E09313h-IS
規格：96T/48T
靈敏度：7.8 pg/ml
檢測范圍：15.6 pg/ml-1000 pg/ml
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
PRF1 Antibodies
PRF1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA018668GA01HU | PRF1 Antibody | Human | ELISA,WB |
| CSB-PA018668LA01HU | PRF1 Antibody | Human | ELISA |
| CSB-PA018668LC01HU | PRF1 Antibody, FITC conjugated | Human | |
| CSB-PA018668LD01HU | PRF1 Antibody, Biotin conjugated | Human | ELISA |
PRF1 for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA018668LA01MO | Prf1 Antibody | Mouse | ELISA, WB |
| CSB-PA018668LB01MO | Prf1 Antibody, HRP conjugated | Mouse | ELISA |
| CSB-PA018668LC01MO | Prf1 Antibody, FITC conjugated | Mouse | |
| CSB-PA018668LD01MO | Prf1 Antibody, Biotin conjugated | Mouse | ELISA |
PRF1 Proteins
PRF1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018668MO | Recombinant Mouse Perforin-1 (PRF1) | Yeast |
| CSB-EP018668MO | Recombinant Mouse Perforin-1 (Prf1) | E.coli |
| CSB-BP018668MO CSB-MP018668MO CSB-EP018668MO-B |
Recombinant Mouse Perforin-1 (PRF1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018668HU CSB-MP018668HU CSB-EP018668HU-B |
Recombinant Human Perforin-1 (PRF1) | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018668HU | Recombinant Human Perforin-1 (PRF1) | E.coli |
| CSB-BP018668HU | Recombinant Human Perforin-1 (PRF1) | Baculovirus |
PRF1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018668RA CSB-BP018668RA CSB-MP018668RA CSB-EP018668RA-B |
Recombinant Rat Perforin-1 (PRF1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018668RA | Recombinant Rat Perforin-1 (Prf1), partial | E.coli |
PRF1 Proteins for Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP349938TDL CSB-EP349938TDL CSB-BP349938TDL CSB-MP349938TDL CSB-EP349938TDL-B |
Recombinant Thermoplasma volcanium Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanococcus maripaludis (strain S2 / LL)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP351670MSB CSB-EP351670MSB CSB-BP351670MSB CSB-MP351670MSB CSB-EP351670MSB-B |
Recombinant Methanococcus maripaludis Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP389400MNP CSB-EP389400MNP CSB-BP389400MNP CSB-MP389400MNP CSB-EP389400MNP-B |
Recombinant Methanococcus maripaludis Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP404375MNN CSB-EP404375MNN CSB-BP404375MNN CSB-MP404375MNN CSB-EP404375MNN-B |
Recombinant Methanobrevibacter smithii Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanococcus vannielii (strain SB / ATCC 35089 / DSM 1224)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP407775MNS CSB-EP407775MNS CSB-BP407775MNS CSB-MP407775MNS CSB-EP407775MNS-B |
Recombinant Methanococcus vannielii Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanococcus maripaludis (strain C7 / ATCC BAA-1331)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP411969MNR CSB-EP411969MNR CSB-BP411969MNR CSB-MP411969MNR CSB-EP411969MNR-B |
Recombinant Methanococcus maripaludis Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP429897MNQ CSB-EP429897MNQ CSB-BP429897MNQ CSB-MP429897MNQ CSB-EP429897MNQ-B |
Recombinant Methanococcus maripaludis Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Thermococcus onnurineus (strain NA1)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP469657TMR CSB-EP469657TMR CSB-BP469657TMR CSB-MP469657TMR CSB-EP469657TMR-B |
Recombinant Thermococcus onnurineus Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP498604HUB CSB-EP498604HUB CSB-BP498604HUB CSB-MP498604HUB CSB-EP498604HUB-B |
Recombinant Halorubrum lacusprofundi Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Thermococcus sibiricus (strain MM 739 / DSM 12597)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP509588TMT CSB-EP509588TMT CSB-BP509588TMT CSB-MP509588TMT CSB-EP509588TMT-B |
Recombinant Thermococcus sibiricus Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP518099DOC CSB-EP518099DOC CSB-BP518099DOC CSB-MP518099DOC CSB-EP518099DOC-B |
Recombinant Archaeoglobus fulgidus Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP521420MSR CSB-EP521420MSR CSB-BP521420MSR CSB-MP521420MSR CSB-EP521420MSR-B |
Recombinant Methanothermobacter thermautotrophicus Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP523929FHX CSB-EP523929FHX CSB-BP523929FHX CSB-MP523929FHX CSB-EP523929FHX-B |
Recombinant Pyrococcus horikoshii Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP532255HTL CSB-EP532255HTL CSB-BP532255HTL CSB-MP532255HTL CSB-EP532255HTL-B |
Recombinant Halobacterium salinarum Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanococcoides burtonii (strain DSM 6242)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP618728MRY CSB-EP618728MRY CSB-BP618728MRY CSB-MP618728MRY CSB-EP618728MRY-B |
Recombinant Methanococcoides burtonii Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Haloquadratum walsbyi (strain DSM 16790)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP621145HAAE CSB-EP621145HAAE CSB-BP621145HAAE CSB-MP621145HAAE CSB-EP621145HAAE-B |
Recombinant Haloquadratum walsbyi Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanosphaera stadtmanae (strain DSM 3091)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP646720MAAR CSB-EP646720MAAR CSB-BP646720MAAR CSB-MP646720MAAR CSB-EP646720MAAR-B |
Recombinant Methanosphaera stadtmanae Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Pyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Thermococcus kodakaraensis (strain KOD1))
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP686349FHY CSB-EP686349FHY CSB-BP686349FHY CSB-MP686349FHY CSB-EP686349FHY-B |
Recombinant Pyrococcus kodakaraensis Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP688247MRU CSB-EP688247MRU CSB-BP688247MRU CSB-MP688247MRU CSB-EP688247MRU-B |
Recombinant Methanocaldococcus jannaschii Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP713307HTJ CSB-EP713307HTJ CSB-BP713307HTJ CSB-MP713307HTJ CSB-EP713307HTJ-B |
Recombinant Haloarcula marismortui Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP740311PAAB CSB-EP740311PAAB CSB-BP740311PAAB CSB-MP740311PAAB CSB-EP740311PAAB-B |
Recombinant Picrophilus torridus Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP819108MSN CSB-EP819108MSN CSB-BP819108MSN CSB-MP819108MSN CSB-EP819108MSN-B |
Recombinant Methanosarcina mazei Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP837591FHW CSB-EP837591FHW CSB-BP837591FHW CSB-MP837591FHW CSB-EP837591FHW-B |
Recombinant Pyrococcus furiosus Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP841864FHU CSB-EP841864FHU CSB-BP841864FHU CSB-MP841864FHU CSB-EP841864FHU-B |
Recombinant Pyrobaculum aerophilum Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP842955FPM CSB-EP842955FPM CSB-BP842955FPM CSB-MP842955FPM CSB-EP842955FPM-B |
Recombinant Sulfolobus solfataricus Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP848521MSI CSB-EP848521MSI CSB-BP848521MSI CSB-MP848521MSI CSB-EP848521MSI-B |
Recombinant Methanopyrus kandleri Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP881086TND CSB-EP881086TND CSB-BP881086TND CSB-MP881086TND CSB-EP881086TND-B |
Recombinant Thermoplasma acidophilum Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP888112HTM CSB-EP888112HTM CSB-BP888112HTM CSB-MP888112HTM CSB-EP888112HTM-B |
Recombinant Halobacterium salinarum Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 Proteins for Pyrococcus abyssi (strain GE5 / Orsay)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP896010FHV CSB-EP896010FHV CSB-BP896010FHV CSB-MP896010FHV CSB-EP896010FHV-B |
Recombinant Pyrococcus abyssi Peptide chain release factor subunit 1 (prf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRF1 ELISA Kit
PRF1 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09313h | Human Perforin-1 (PRF1/PFP) ELISA kit | serum, plasma, tissue homogenates | 0.078 ng/mL |
| CSB-E09313h-IS | Human Perforin-1 (PRF1/PFP) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates. | 7.8 pg/ml |
PRF1 ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13429m | Mouse Perforin/Pore-forming protein,PF/PFP ELISA Kit | serum, plasma, cell culture supernates | 1.95 pg/mL |
