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PROS1

PROS1,全稱為蛋白S(Protein S),是一種重要的抗凝蛋白,在血液凝固過程中發揮著關鍵作用。蛋白S具有多種別名,包括PROS、PS21、PS22、PS23、PS24、PS25、PS26、PS26、Vitamin K-dependent plasma protein S以及Vitamin K-dependent protein S等。蛋白S主要由肝臟合成,然后分布到血漿中,其中約60%與C4b結合蛋白復合物結合,約40%以游離形式存在,而只有游離形式的蛋白S才能作為活化蛋白C(APC)的輔因子,參與抗凝過程。蛋白S缺乏會導致靜脈血栓栓塞癥(VTE)的風險顯著增加,因此,蛋白S缺乏癥是一種常染色體顯性遺傳病。目前,針對蛋白S缺乏癥的治療方法主要包括抗凝治療和蛋白S替代治療。此外,研究人員也在探索蛋白S作為生物標志物的潛力,用于哮喘等疾病的診斷和預后評估。

熱銷產品

Recombinant Human Vitamin K-dependent protein S (PROS1) (CSB-EP018754HU)

驗證數據

CSB-EP018754HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PROS1 Antibody (CSB-PA018754LA01HU)

驗證數據

CSB-PA018754LA01HU

IHC image of CSB-PA018754LA01HU diluted at 1:200 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA018754LA01HU

IHC image of CSB-PA018754LA01HU diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA018754LA01HU

Immunofluorescence staining of HepG2 cells with CSB-PA018754LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Human Protein S ELISA Kit (CSB-E09903h)

驗證數據

CSB-E09903h 標準曲線

貨號:CSB-E09903h

規格:96T/48T

靈敏度:0.78 ng/mL

檢測范圍:3.12 ng/mL-200 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PROS1 Antibodies

PROS1 for Homo sapiens (Human)

PROS1 Proteins

PROS1 Proteins for Oryctolagus cuniculus (Rabbit)

PROS1 Proteins for Homo sapiens (Human)

PROS1 Proteins for Bos taurus (Bovine)

PROS1 Proteins for Rattus norvegicus (Rat)

PROS1 Proteins for Bacillus thuringiensis (strain Al Hakam)

PROS1 Proteins for Rhodococcus sp. (strain RHA1)

PROS1 Proteins for Clostridium difficile (strain 630)

PROS1 Proteins for Macaca mulatta (Rhesus macaque)

PROS1 Proteins for Anaeromyxobacter dehalogenans (strain 2CP-C)

PROS1 Proteins for Bacillus cereus (strain ZK / E33L)

PROS1 Proteins for Bacillus thuringiensis subsp. konkukian (strain 97-27)

PROS1 Proteins for Bacillus cereus (strain ATCC 10987)

PROS1 Proteins for Bacillus anthracis

PROS1 Proteins for Bacillus cereus (strain ATCC 14579 / DSM 31)

PROS1 Proteins for Streptomyces avermitilis

PROS1 ELISA Kit

PROS1 ELISA Kit for Monkey

PROS1 ELISA Kit for Mus musculus (Mouse)

PROS1 ELISA Kit for Homo sapiens (Human)