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PTK7

PTK7,即蛋白酪氨酸激酶7,別名CCK4。它是一種由PTK7基因編碼的非受體型蛋白酪氨酸激酶,主要在發(fā)育和免疫反應中發(fā)揮作用。PTK7的作用機制涉及與多種蛋白質(zhì)相互作用,參與細胞極性、遷移和增殖等過程,特別是在胚胎發(fā)育和腫瘤細胞的侵襲中。PTK7參與了細胞內(nèi)多種信號通路的調(diào)控,包括Wnt/PCP和經(jīng)典Wnt信號通路,影響細胞的極性、運動、遷移和侵襲。此外,PTK7的功能異常與某些疾病有關,如腫瘤的發(fā)生和發(fā)展。

熱銷產(chǎn)品

Recombinant Human Inactive tyrosine-protein kinase 7(PTK7),partial (Active) (CSB-MP622651HU2)

驗證數(shù)據(jù)

CSB-MP622651HU2

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP622651HU2

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human PTK7 at 2 μg/ml can bind Anti-PTK7 recombinant antibody (CSB-RA622651MA1HU). The EC50 is 0.3675 - 0.65842 ng/mL.

CSB-MP622651HU2

The purity of PTK7 was greater than 95% as determined by SEC-HPLC

PTK7 Antibody (CSB-PA018996LA01HU)

驗證數(shù)據(jù)

CSB-PA018996LA01HU

IHC image of CSB-PA018996LA01HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human Inactive tyrosine-protein kinase 7(PTK7) ELISA kit (CSB-EL018996HU)

驗證數(shù)據(jù)

CSB-EL018996HU 標準曲線

貨號:CSB-EL018996HU

規(guī)格:96T/48T

靈敏度:3.125 pg/mL

檢測范圍:12.5 pg/mL-800 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PTK7 Antibodies

PTK7 for Homo sapiens (Human)

PTK7 Proteins

PTK7 Proteins for Homo sapiens (Human)

PTK7 Proteins for Mus musculus (Mouse)

PTK7 Proteins for Gallus gallus (Chicken)

PTK7 ELISA Kit

PTK7 ELISA Kit for Homo sapiens (Human)