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RASSF5

Ras association domain-containing protein 5 is a protein in humans that is encoded by RASSF5 gene. Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

RASSF5 Antibodies

RASSF5 for Homo sapiens (Human)

RASSF5 Proteins

RASSF5 Proteins for Rattus norvegicus (Rat)

RASSF5 Proteins for Mus musculus (Mouse)

RASSF5 Proteins for Homo sapiens (Human)