RTN4

RTN4，即Reticulon 4，別名Neurite Growth Inhibitor 220、My043等。RTN4是一種在多種組織中表達的內(nèi)質(zhì)網(wǎng)相關蛋白，尤其在神經(jīng)系統(tǒng)中，它作為一種神經(jīng)突起生長抑制劑，參與調(diào)節(jié)神經(jīng)再生。RTN4的作用機制涉及調(diào)節(jié)內(nèi)質(zhì)網(wǎng)形態(tài)，影響內(nèi)質(zhì)網(wǎng)腔內(nèi)物質(zhì)的運輸，包括鈣離子等，進而影響細胞功能。RTN4在神經(jīng)系統(tǒng)發(fā)育、神經(jīng)元存活、細胞骨架調(diào)節(jié)以及腫瘤發(fā)展等方面都具有重要作用。研究發(fā)現(xiàn)，RTN4的表達與多種癌癥的發(fā)生發(fā)展相關，例如在肺癌、乳腺癌、宮頸癌和腎癌中，較低的RTN4表達與患者生存率的提高相關。此外，RTN4還參與調(diào)節(jié)血管生成和神經(jīng)修復過程。在膠質(zhì)瘤中，RTN4的表達與腫瘤的惡性增殖行為相關，可能通過影響細胞周期相關蛋白的表達來調(diào)控膠質(zhì)瘤細胞的增殖。

熱銷產(chǎn)品

RTN4 Recombinant Monoclonal Antibody (CSB-RA878853MA1HU)

驗證數(shù)據(jù)

Overlay Peak curve showing A549 cells stained with CSB-RA878853MA1HU (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10⁶cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-human IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was human IgG (1ug/1*10⁶cells) used under the same conditions. Acquisition of >10,000 events was performed.

Human Reticulon-4(RTN4) ELISA kit (CSB-EL020572HU)

驗證數(shù)據(jù)

貨號：CSB-EL020572HU

規(guī)格：96T/48T

靈敏度：11.75 pg/mL

檢測范圍：46.88 pg/mL-3000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

RTN4 Antibody

RTN4 Protein

RTN4 ELISA Kit

RTN4 Antibodies

RTN4 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應性	應用類型
CSB-PA020572GA01HU	RTN4 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA003461	RTN4 Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA931699	RTN4 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA054695	RTN4 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-RA878853MA1HU	RTN4 Recombinant Monoclonal Antibody	Human	ELISA, FC

RTN4 Proteins

RTN4 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP860001MO CSB-EP860001MO CSB-BP860001MO CSB-MP860001MO CSB-EP860001MO-B	Recombinant Mouse Reticulon-4 (Rtn4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

RTN4 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP862389RA CSB-EP862389RA CSB-BP862389RA CSB-MP862389RA CSB-EP862389RA-B	Recombinant Rat Reticulon-4 (Rtn4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

RTN4 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP878853HU CSB-EP878853HU CSB-BP878853HU CSB-MP878853HU CSB-EP878853HU-B	Recombinant Human Reticulon-4 (RTN4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli