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SNAI2

Zinc finger protein SNAI2 is a protein in humans that is encoded by SNAI2 gene. Transcriptional repressor that modulates both activator-dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role in mediating RAF1-induced transcriptional repression of the TJ protein, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells (By similarity). Represses BRCA2 expression by binding to its E2-box-containing silencer and recruiting CTBP1 and HDAC1 in breast cells. In epidermal keratinocytes, binds to the E-box in ITGA3 promoter and represses its transcription.

SNAI2 Antibodies

SNAI2 for Homo sapiens (Human)

SNAI2 Proteins

SNAI2 Proteins for Mus musculus (Mouse)

SNAI2 Proteins for Rattus norvegicus (Rat)

SNAI2 Proteins for Homo sapiens (Human)

SNAI2 Proteins for Bos taurus (Bovine)

SNAI2 Proteins for Xenopus laevis (African clawed frog)