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SSR1

SSR1,全稱為生長抑素受體1蛋白,是一種在細(xì)胞內(nèi)質(zhì)網(wǎng)功能調(diào)節(jié)中發(fā)揮作用的蛋白質(zhì)。它通過與TRAP蛋白結(jié)合,參與內(nèi)質(zhì)網(wǎng)膜的功能調(diào)節(jié)。TRAP蛋白在將鈣結(jié)合到內(nèi)質(zhì)網(wǎng)膜上的復(fù)合物中發(fā)揮作用,從而調(diào)節(jié)駐留內(nèi)質(zhì)網(wǎng)蛋白的保留。SSR1蛋白可能在易位過程完成后的易位裝置回收中發(fā)揮作用,或者充當(dāng)膜結(jié)合伴侶,促進(jìn)易位蛋白質(zhì)的折疊。TRAP蛋白的異四聚體由TRAP-α、TRAP-β、TRAP-δ和TRAP-gamma組成,與棕櫚酰化鈣聯(lián)蛋白相互作用,這種相互作用對(duì)于糖基化蛋白的有效折疊至關(guān)重要。SSR1蛋白的相關(guān)疾病包括血清素綜合癥,其癥狀包括高燒、激動(dòng)、反射亢進(jìn)、顫抖、瞳孔放大及腹瀉等。SSR1蛋白的藥物研發(fā)進(jìn)展包括新型核酸藥物及靶向核酸的藥物研發(fā),以及兒童抗腫瘤藥物研發(fā)鼓勵(lì)試點(diǎn)計(jì)劃等。

熱銷產(chǎn)品

Recombinant Human Somatostatin receptor type 1 (SSTR1)-VLPs (CSB-MP022724HU)

驗(yàn)證數(shù)據(jù)

CSB-MP022724HU

CSB-MP022724HU is detected by Mouse anti-6*His monoclonal antibody.

SSTR1 Antibody (CSB-PA793008)

驗(yàn)證數(shù)據(jù)

CSB-PA793008

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA793008(SSTR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA793008

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA793008(SSTR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

SSR1 Antibodies

SSR1 for Homo sapiens (Human)

SSR1 Proteins

SSR1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

SSR1 Proteins for Homo sapiens (Human)

SSR1 Proteins for Oryctolagus cuniculus (Rabbit)

SSR1 Proteins for Bos taurus (Bovine)

SSR1 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

SSR1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

SSR1 Proteins for Dictyostelium discoideum (Slime mold)

SSR1 Proteins for Pongo abelii (Sumatran orangutan)

SSR1 Proteins for Rattus norvegicus (Rat)

SSR1 Proteins for Mus musculus (Mouse)