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tst

TST,即硫氧還蛋白相互作用蛋白(也常被叫做TXNIP或VDUP1)是一種與細(xì)胞內(nèi)氧化狀態(tài)調(diào)節(jié)相關(guān)的蛋白。它能和硫氧還蛋白結(jié)合,改變后者的活性,進(jìn)而影響細(xì)胞應(yīng)對氧化壓力的能力。在日常代謝過程中,這種蛋白的表達(dá)水平會隨血糖變化波動,和葡萄糖的利用關(guān)系密切——當(dāng)血糖升高時,它的含量往往上升,可能干擾胰島素的正常作用。
TST和多種疾病存在關(guān)聯(lián):比如2型糖尿病患者體內(nèi),它的水平常出現(xiàn)異常,可能加重胰島素抵抗的情況;部分腫瘤中,它的表達(dá)變化也被觀察到,與細(xì)胞過度增殖或凋亡失衡有關(guān)。目前針對它的藥物研究還處于早期階段,一些實(shí)驗(yàn)室正在嘗試開發(fā)能調(diào)節(jié)其功能的小分子物質(zhì),希望用于改善代謝紊亂或抑制腫瘤生長。

熱銷產(chǎn)品

TST Antibody (CSB-PA620980LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA620980LA01HU

Western Blot
Positive WB detected in: Rat liver tissue
All lanes: TST antibody at 5μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 34 kDa
Observed band size: 34 kDa

CSB-PA620980LA01HU

IHC image of CSB-PA620980LA01HU diluted at 1:400 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA620980LA01HU

IHC image of CSB-PA620980LA01HU diluted at 1:400 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human Thiosulfate sulfurtransferase(TST) ELISA kit (CSB-EL025197HU)

驗(yàn)證數(shù)據(jù)

CSB-EL025197HU 標(biāo)準(zhǔn)曲線

貨號:CSB-EL025197HU

規(guī)格:96T/48T

靈敏度:3.9 pg/mL

檢測范圍:15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

tst Antibodies

tst for Homo sapiens (Human)

tst Proteins

tst Proteins for Homo sapiens (Human)

tst ELISA Kit

tst ELISA Kit for Homo sapiens (Human)