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Kng1 Antibody

Rare Species
  • 中文名稱：
    Kng1兔多克隆抗體
  • 貨號：
    CSB-PA012479LA01RA
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Rattus norvegicus (Rat) Kng1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Kng1 antibody; Kng antibody; Kininogen-1 [Cleaved into: Kininogen-1 heavy chain; Bradykinin; Kininogen-1 light chain] antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Rat
  • 免疫原：
    Recombinant Rat Kininogen-1 protein (2-110AA)
  • 免疫原種屬：
    Rattus norvegicus (Rat)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，Kng1 Antibody (CSB-PA012479LA01RA)，的標記方式是Non-conjugated。對于Kng1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應用
    HRP CSB-PA012479LB01RA Kng1 Antibody, HRP conjugated ELISA
    FITC CSB-PA012479LC01RA Kng1 Antibody, FITC conjugated
    Biotin CSB-PA012479LD01RA Kng1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
  • 基因功能參考文獻：
    1. High-molecular-weight kininogen and its peptide fragments modulate arterial thrombosis after arterial injury. PMID: 17293494
  • 亞細胞定位：
    Secreted, extracellular space.
  • 組織特異性：
    Plasma.
  • 數(shù)據(jù)庫鏈接：